专利名称：Highly efficient delivery of a large
therapeutic mass aerosol
发明人：David A. Edwards,Richard P. Batvcky,Lloyd
Johnston
申请号：US10681416申请日：20031008公开号：US06921528B2公开日：20050726
摘要：A method for delivering a therapeutic dose of a bioactive agent to thepulmonary system, in a single, breath-activated step, comprises administering from areceptacle enclosing a mass of particles, to a subject's respiratory tract, particles whichhave a tap density of less than 0.4 g/cmand deliver at least about 50% of the mass ofparticles. Another method of delivering a therapeutic dose of a bioactive agent to thepulmonary system, in a single breath, includes administering from a receptacle enclosinga mass of particles, to a subject's respiratory tract, particles which have a tap density of atleast 0.4 g/cmand deliver at least about 10 milligrams of the bioactive agent. Thereceptacle can have a volume of at least 0.37 cm.
申请人：David A. Edwards,Richard P. Batvcky,Lloyd Johnston
地址：Boston MA US,Auburndale MA US,Belmont MA US
国籍：US,US,US
代理机构：Elmore, Craig & Vanstone, P.C.
代理人：Anne I. Craig,Carolyn S. Elmore
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