专利名称：THE USE OF ANTIGESTAGENS FOR
INHIBITING ACCELERATED ENDOMETRIALMATURATION DURING INFERTILITYTREATMENT
发明人：HEGELE-HARTUNG, Christa,HESS-STUMPP,
Holger,BEIER, Henning, M.,KRUSCHE, Claudia
申请号：EP02722637.2申请日：20020109公开号：EP1365765A2公开日：20031203
摘要：Refers to the use of a progesterone receptor antagonist of 17th -fluoroalquilado formula I where R1 is MethylEthyl; R2 is cnfmho where n is greater than 1- 6; M + 1 and M = 2n + 1; R3 is a free hydroxyl Group, Esterified and etherified, each R4and R5 are h, together form an additional ligation.A methylene Group; St is a steroidalring.Preferred compounds are 11\ß (4-acetylphenyl) - hydroxy - (17\ß 17th1,1,2,2,2 - pentafluoroetil estr) - 4 - [17\ß Ona, 4 '- hydroxy - 3 - oxo - (1,1,2,2,2 17th -pentafluoroetil estr) - 4 - in - 11\ß - il] [1.1 '- biphenyl] - 4 - carbonitrilo, amongothers.These compounds are administered in an amount of 0.1 mg to 2 mg per day in asingle subject during the post ovulatory phase of the Cycle and endometrial are helpfulfor improving Fertility
申请人：SCHERING AKTIENGESELLSCHAFT
地址：13342 Berlin DE
国籍：DE
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