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METHOD FOR THE PRODUCTION OF RECOMBINANT PEPTIDES

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专利名称:METHOD FOR THE PRODUCTION OF

RECOMBINANT PEPTIDES WITH A LOWAMOUNT OF TRISULFIDES

发明人:HEMMENDORFF, Barbro,CASTAN,

Andreas,PERSSON, Anders

申请号:EP99933442.8申请日:19990705公开号:EP1095055B1公开日:20030903

摘要:The invention relates to a method for the production of recombinant peptideswith a low amount of trisulfides which is characterized by the addition of a metal saltduring or after the fermentation step and to a method for reduction of the amount oftrisulfides in the production of recombinant peptides, characterized by the addition of ametal salt during or after fermentation. The peptide is preferably human growthhormone and the salt preferably a potassium or sodium phosphate.

申请人:PHARMACIA AB

地址:SE

国籍:SE

代理机构:Tannerfeldt, Sigrid Agneta

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