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METHODS FOR PREVENTING OR TREATING INFECTIOUS DISE

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专利名称:METHODS FOR PREVENTING OR TREATING

INFECTIOUS DISEASES CAUSED BYEXTRACELLULAR MICROORGANISMS,INCLUDING ANTIMICROBIAL-RESISTANTSTRAINS THEREOF, USING GALLIUMCOMPOUNDS

发明人:Daniel P. Perl,Sharon Moalem申请号:US15259100申请日:20160908

公开号:US20160375056A1公开日:20161229

摘要:The present invention relates to methods for preventing or treating infectiousdiseases caused by extracellular microorganisms, such as bacteria and fungi, by

systemically administering to a patient a compound containing gallium. The extracellularmicroorganisms targeted by the present methods include methicillin-resistant (MRSA),vancomycin-resistant (VRE), O157:H7, fluoroquinolone-resistant , and the like.

Furthermore, in the present methods, gallium compounds can be co-administered withone or more conventional antimicrobial agents to treat infectious diseases with reducedrisks of creating multi-drug resistant pathogens. The methods of the present invention isalso applicable to those microorganisms, such as ulcer-causing , complete eradication ofwhich so far has been difficult to achieve.

申请人:MOUNT SINAI SCHOOL OF MEDICINE

地址:NEW YORK NY US

国籍:US

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