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Thiophene-2-carboxylic-acid derivatives and proces

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专利名称:Thiophene-2-carboxylic-acid derivatives and

process for their preparation

发明人:BINDER, DIETER, PROF. DR.,NOE, CHRISTIAN,

MAG.PHARM.DIPL.ING.DR.

申请号:EP83890183.3申请日:19831018公开号:EP0109381B1公开日:19860730

摘要:new thiophen 2 carbons\äurederivate the general formula what r inposition 3 or 4 of the thiophenkerns hydrogen, methyl, chtor or bromine and r1hydrogen or c1 - c4 - alkyl meanand its pharmaceutical acceptable acid or

basenadditionssalze possess a strong hemmungswirkung on thromboxansynthetase andare therefore suitable for the treatment of diseases.the thromboxane a2 caused. forexample, inflammation, high blood pressure, thrombus, gehirnscniag.asthma, angina,ischemic heart disease, schamische seizures, migraine and vascular complications ofdiabetes.

申请人:LAEVOSAN-GESELLSCHAFT M.B.H.

地址:Estermannstrasse 17 A-4020 Linz AT

国籍:AT

代理机构:Pawloy, Heinrich, Dr.

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