METHOD FOR PRODUCING L-2-AMINO-4-(HYDROXYMETHYLPHO

专利名称：METHOD FOR PRODUCING L-2-AMINO-4-(HYDROXYMETHYLPHOSPHINYL)-BUTANOIC ACID

发明人：MINOWA, Nobuto,NAKANISHI,

Nozomu,MITOMI, Masaaki

申请号：EP06730167.1申请日：20060328公开号：EP1864989A1公开日：20071212

摘要：Disclosed is a method for efficiently and highly selectively producing L-2-amino-4-(hydroxymethylphosphinyl)-butanoic acid, which is useful as a herbicide, through acatalytic asymmetric synthesis reaction. Specifically disclosed is a method for producingL-2-amino-4-(hydroxymethylphosphinyl)-butanoic acid which is a dehydroamino acid issubjected to an asymmetric hydrogenation by using a rhodium catalyst represented bythe formula (2) below and having an optically active cyclic phosphine ligand, and then theresulting product is subjected to hydrolysis: [Rh(R)(L)]X (2) [where R represents 1,5-cyclooctadien or norbornadien; L represents a substance represented by the followingformula (6): (wherein R and R respectively represent a C alkyl group; R and R respectivelyrepresent hydrogen atom or hydroxyl group; and Y represents a group selected fromgroups represented by the following formula (7): (where Me represents methyl group)).].

申请人：Meiji Seika Kaisha, Ltd.

地址：4-16, Kyobashi 2-chome, Chuo-ku Tokyo 104-8002 JP

国籍：JP

代理机构：Polypatent

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