2-ethyl and 2-ethylidene-19-nor-vitamin D compound

专利名称：2-ethyl and 2-ethylidene-19-nor-vitamin D

compounds

发明人：Hector F. DeLuca,Rafal R. Sicinski申请号：US11191791申请日：20050728公开号：US07141558B2公开日：20061128

摘要：Biologically active 19-nor vitamin D analogs substituted at C-2 in the A-ring withan ethylidene or an ethyl group. These compounds have preferential activity onmobilizing calcium from bone and either high or normal intestinal calcium transportactivity which allows their in vivo administration for the treatment of metabolic bonediseases where bone loss is a major concern. These compounds are also characterized byhigh cell differentiation activity.

申请人：Hector F. DeLuca,Rafal R. Sicinski

地址：Deerfield WI US,Warsaw PL

国籍：US,PL

代理机构：Andrus, Sceales, Starke & Sawall, LLP

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