专利名称：Nanocoating for improving biocompatibility
of medical implants
发明人：Liping Tang申请号：US10896376申请日：20040721
公开号：US20050084513A1公开日：20050421
摘要：A coating for an implant surface comprising one or more nanoparticles of lessthan or equal to 500 nanometers and an implant surface capable of receiving the
nanoparticles, the implant selected from the group consisting of metal, carbon, graphite,polymer, protein, nucleic acid, microorganisms, hydrogel, liquid, porous and polymerblend particles, and combinations thereof. The coating promotes characteristics on theimplant surface such as reducing protein unfolding, preventing inflammatory and fibroticcell accumulation, reducing the number of such cell attachment sites and preventingother adverse biological reactions. The coating may be applied on any material viaphysical and/or chemical binding. The coating may further comprise a surfactant and mayinclude a tag, adsorbed, absorbed or incorporated onto the nanoparticle. The coating onan implant surface is used for purposes that may be cosmetic, therapeutic, preventative,reconstructive, monitoring and replacement. The coating may also be used for in vitropurposes.
申请人：Liping Tang
地址：Arlington TX US
国籍：US
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