专利名称：MEDICAMENT FOR TREATMENT OF
NEUROPATHIES
发明人：LILLY ICOS LLC申请号：EP00943518.1申请日：20000727公开号：EP1220672A1公开日：20020710
摘要：Compounds of formula (I) in which R1 = C¿1-6? alkyl, optionally halosubstituted;R?2¿ = H, C¿1-4? alkyl, optionally halosubstituted or replaced by halogen; R?3¿ = C¿2-4?alkyl, optionally halosubstituted; R?4 = SO¿2NR5R&, CO2R7 or halogen, C¿2-4? alkenyl,optionally substituted with NR?5R6, SONR5R6, CONR5R6, CO2R7¿ or halogen, C¿2-4?alkanoyl, optionally substituted with NR?5R6, SONR5R6, CONR5R6, CO¿2R7 or halogen;R?5 and R6¿ = independently H or C1-4 alkyl, or, together with the N atom to which theyare attached, a pyrrolidino, piperidino, morpholino, 4-(NR8)-1-piperazinyl or 1-imidazolylring optionally substituted with one or two C¿1-4? alkyl groups; R?7 =H, C1-4¿ alkyl,optionally fluorosubstituted, and R?8 =H, C1-3¿ alkyl or hydroxyalkyl with 1 - 4 C atoms,or the pharmaceutically acceptable salts thereof are useful for the chemotherapeutictreatment of neuropathies.
申请人：LAREIDA, JUERG
地址：Vordere Vorstadt 16 5000 Aarau CH
国籍：CH
代理机构：Ritscher, Thomas, Dr.
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